Post by seniorcitizen007 on Nov 9, 2022 3:18:19 GMT
www.ncbi.nlm.nih.gov/pmc/articles/PMC5976205/
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice
Extract:
An increased abundance of E. cloacae in humans was initially linked to obesity in a case study by Zhao et al., where the reduction of intestinal E. cloacae strain B29, from 35% to non-detectable levels, was associated with a parallel reduction in endotoxin load and a significant weight loss in a patient with morbid obesity [14]. Furthermore, the same bacterial strain, isolated from this patient, initiated obesity and triggered inflammation when introduced to HFD germ-free mice [14,19]. The above-mentioned studies suggest that E. cloacae may contribute to obesity, possibly through an endotoxin or flagella-induced inflammation-mediated mechanism.
My comments
Obese people usually have a significant degree of inflammation (detectable by blood tests). In the unit where I have my dialysis there are a LOT of obese people. The nurses move from patient to patient. I have, on MANY occasions, developed a fever during my dialysis sessions. Lab tests of my blood (when they bothered to do them) detected the presence of Enterobacter cloacae. If I was eating a high fat diet I'd probably put on weight.
Other species of intestinal bacteria have been linked to obesity.
On every occasion when I've developed a fever I've refused antibiotics (except the first occasion. when I got a toxic reaction to the gentamicin they gave me). I take a herbal antibiotic/immune stimulant ... which sorts things within a few hours. What I take is being researched as an alternative to antibiotics to treat antibiotic resistant bacteria.
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice
Extract:
An increased abundance of E. cloacae in humans was initially linked to obesity in a case study by Zhao et al., where the reduction of intestinal E. cloacae strain B29, from 35% to non-detectable levels, was associated with a parallel reduction in endotoxin load and a significant weight loss in a patient with morbid obesity [14]. Furthermore, the same bacterial strain, isolated from this patient, initiated obesity and triggered inflammation when introduced to HFD germ-free mice [14,19]. The above-mentioned studies suggest that E. cloacae may contribute to obesity, possibly through an endotoxin or flagella-induced inflammation-mediated mechanism.
My comments
Obese people usually have a significant degree of inflammation (detectable by blood tests). In the unit where I have my dialysis there are a LOT of obese people. The nurses move from patient to patient. I have, on MANY occasions, developed a fever during my dialysis sessions. Lab tests of my blood (when they bothered to do them) detected the presence of Enterobacter cloacae. If I was eating a high fat diet I'd probably put on weight.
Other species of intestinal bacteria have been linked to obesity.
On every occasion when I've developed a fever I've refused antibiotics (except the first occasion. when I got a toxic reaction to the gentamicin they gave me). I take a herbal antibiotic/immune stimulant ... which sorts things within a few hours. What I take is being researched as an alternative to antibiotics to treat antibiotic resistant bacteria.
