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Post by Baron von Lotsov on May 28, 2023 19:27:43 GMT
Quick summary:
The biology of the body is very similar across species as a lot has a common origin back in evolution. In fact there is a fair bit of the biology of plants that also goes on in mammals because the same rules of biochemistry apply. Many mammals hibernate for winter. To do this need an instinctive behaviour of obsessive eating, even if that involves danger in a kind of thoughtless and compulsive way. The foraging behaviour would involve eating fruit as this is ripe on the trees as the weather starts to turn cold. Ripened fruit is sweet because it contains fructose. If the mammal did not do this enough before hibernation it would not survive the winter, hence the body developed a mechanism where upon eating fructose this triggers a biological response that redirects the process of the body breaking down the fructose to create ATP which is the molecule that carries energy around the body and instead tells it to convert to fat. Furthermore this lack of energy reduces the energy supply going to the brain, but it does so in a selective way, where some areas useful for foraging actually get an enhanced supply of blood like the visual processing, where the frontal cortex, used to control compulsion with reason is inhibited. The constant reduced energy to the brain causes the brain to shrink and eventually you end up with Alzheimer's disease.
This has just been discovered, since the original theory on the disease was wrong in it mistook a symptom for the cause and got nowhere in the treatment. Here is the guy who put them right on it.
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Post by Ripley on May 28, 2023 20:40:03 GMT
Quick summary:
The biology of the body is very similar across species as a lot has a common origin back in evolution. In fact there is a fair bit of the biology of plants that also goes on in mammals because the same rules of biochemistry apply. Many mammals hibernate for winter. To do this need an instinctive behaviour of obsessive eating, even if that involves danger in a kind of thoughtless and compulsive way. The foraging behaviour would involve eating fruit as this is ripe on the trees as the weather starts to turn cold. Ripened fruit is sweet because it contains fructose. If the mammal did not do this enough before hibernation it would not survive the winter, hence the body developed a mechanism where upon eating fructose this triggers a biological response that redirects the process of the body breaking down the fructose to create ATP which is the molecule that carries energy around the body and instead tells it to convert to fat. Furthermore this lack of energy reduces the energy supply going to the brain, but it does so in a selective way, where some areas useful for foraging actually get an enhanced supply of blood like the visual processing, where the frontal cortex, used to control compulsion with reason is inhibited. The constant reduced energy to the brain causes the brain to shrink and eventually you end up with Alzheimer's disease.
This has just been discovered, since the original theory on the disease was wrong in it mistook a symptom for the cause and got nowhere in the treatment. Here is the guy who put them right on it.
That was quite interesting. It is true that sugar makes you hungry, as you will know if you give it up and suddenly find yourself less hungry. I recently read a book by neuroscientist Lisa Genova titled "Remember' in which she says that deep sleep is like a power wash for your brain. During deep sleep, your glial cells flush away metabolic debris that accumulated in your synapses while you were awake. One of the most important things deep sleep clears away is amyloid. If you get too little sleep, the glial cells won't have had enough time to finish the job and you will wake up in the morning with amyloid left over in your synapses from the previous day - an amyloid hangover if you will. Genova says that a single night of sleep deprivation can lead to an increase in amyloid and tau, another predictive biomarker for Alzheimer's, in cerebral fluid. Insufficient sleep is another likely risk factor in the development of Alzheimer's. |
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Post by Baron von Lotsov on May 28, 2023 21:20:02 GMT
Quick summary:
The biology of the body is very similar across species as a lot has a common origin back in evolution. In fact there is a fair bit of the biology of plants that also goes on in mammals because the same rules of biochemistry apply. Many mammals hibernate for winter. To do this need an instinctive behaviour of obsessive eating, even if that involves danger in a kind of thoughtless and compulsive way. The foraging behaviour would involve eating fruit as this is ripe on the trees as the weather starts to turn cold. Ripened fruit is sweet because it contains fructose. If the mammal did not do this enough before hibernation it would not survive the winter, hence the body developed a mechanism where upon eating fructose this triggers a biological response that redirects the process of the body breaking down the fructose to create ATP which is the molecule that carries energy around the body and instead tells it to convert to fat. Furthermore this lack of energy reduces the energy supply going to the brain, but it does so in a selective way, where some areas useful for foraging actually get an enhanced supply of blood like the visual processing, where the frontal cortex, used to control compulsion with reason is inhibited. The constant reduced energy to the brain causes the brain to shrink and eventually you end up with Alzheimer's disease.
This has just been discovered, since the original theory on the disease was wrong in it mistook a symptom for the cause and got nowhere in the treatment. Here is the guy who put them right on it.
That was quite interesting. It is true that sugar makes you hungry, as you will know if you give it up and suddenly find yourself less hungry. I recently read a book by neuroscientist Lisa Genova titled "Remember' in which she says that deep sleep is like a power wash for your brain. During deep sleep, your glial cells flush away metabolic debris that accumulated in your synapses while you were awake. One of the most important things deep sleep clears away is amyloid. If you get too little sleep, the glial cells won't have had enough time to finish the job and you will wake up in the morning with amyloid left over in your synapses from the previous day - an amyloid hangover if you will. Genova says that a single night of sleep deprivation can lead to an increase in amyloid and tau, another predictive biomarker for Alzheimer's, in cerebral fluid. Insufficient sleep is another likely risk factor in the development of Alzheimer's. Yes I've just looked that up and there are some 50 diseases amyloids can cause with Alzheimer's being one of them. It seems to be particularly bad if deep sleep is interrupted regarding malfunctioning brains in my experience. I've religiously ensured I get my full natural sleep and are fastidious about it, but I do confess to a bit of sugar and salt. I've never been a junk food addict, but even so there is a lot of this fructose about in commercial food. Compulsive eating of it would increase sales. |
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Post by Ripley on May 28, 2023 22:26:02 GMT
That was quite interesting. It is true that sugar makes you hungry, as you will know if you give it up and suddenly find yourself less hungry. I recently read a book by neuroscientist Lisa Genova titled "Remember' in which she says that deep sleep is like a power wash for your brain. During deep sleep, your glial cells flush away metabolic debris that accumulated in your synapses while you were awake. One of the most important things deep sleep clears away is amyloid. If you get too little sleep, the glial cells won't have had enough time to finish the job and you will wake up in the morning with amyloid left over in your synapses from the previous day - an amyloid hangover if you will. Genova says that a single night of sleep deprivation can lead to an increase in amyloid and tau, another predictive biomarker for Alzheimer's, in cerebral fluid. Insufficient sleep is another likely risk factor in the development of Alzheimer's. Yes I've just looked that up and there are some 50 diseases amyloids can cause with Alzheimer's being one of them. It seems to be particularly bad if deep sleep is interrupted regarding malfunctioning brains in my experience. I've religiously ensured I get my full natural sleep and are fastidious about it, but I do confess to a bit of sugar and salt. I've never been a junk food addict, but even so there is a lot of this fructose about in commercial food. Compulsive eating of it would increase sales. You should be okay as long as you don't consume excessive amounts of those substances. |
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Post by seniorcitizen007 on May 29, 2023 17:19:31 GMT
A high fructose diet affects the activity of the hypothalamus–pituitary–gonadal (HPG) axis leading to a reduction in plasma testosterone levels and sperm motility
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Post by Bentley on May 29, 2023 17:21:38 GMT
A high fructose diet affects the activity of the hypothalamus–pituitary–gonadal (HPG) axis leading to a reduction in plasma testosterone levels and sperm motility I thought that was Watneys red barrel. |
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